研究内容
- 食品质量分析
- 食品安全与鉴伪
- 化学计量学
- 指纹图谱
- 色谱、质谱学
承担项目
- 国家自然科学青年基金项目“基于UPLC-MS与UPC2-MS多元指纹图谱技术的牛乳鉴伪方法研究”（主持）
- 雀巢产品技术援助有限公司“流动注射指纹质谱在牛乳与食用油掺假鉴定中的适用性研究” （主持）
- jk萝莉 “医工交叉”研究基金“低聚原花青素对年龄相关性黄斑变性保护作用的研究”（主要参与人）
- 企业横向 鲜烟叶主要营养成分的快速便携试剂盒检测技术研究 （主持）
论文
- Zhang, M.; Wang, C.; Zhu, L.; Zhu, H.; Zheng, W.; Lu, W.; Niu, Y.; Zhang, Y.; Gao, B.; Yu, L. L., Integrated metabolomic and transcriptomic analyses of mouse liver reveals the in vivo toxicity and mechanisms of individual and combined toxicants formed in the thermal processing of high-fat diets. Journal of Agricultural and Food Chemistry 2025, 73 (21), 13047−13064.
- Li, W.; Sha, Y.; Xiong, J.; Chen, Y.; Zhang, Y.; Zhang, J.; Xu, L.*; Lu, W.*, LIGHt-based rapid detection of starch in tobacco leaves by smartphone sensing. Scientific Reports 2025, 15 (1), 6689.
- Wang, C.; Zhu, H.; Zhang, M.; Zhu, L.; Zheng, W.; Lu, W.; Niu, Y.; Zhang, Y.; Gao, B.; Yu, L. L., Ninety-day subchronic toxicology of individual and combined toxicants from the thermal processing of lipid-rich foods. Journal of Agricultural and Food Chemistry 2024, 72 (50), 28122−28137.
- Chen, Y.; Yu, W.; Niu, Y.; Li, W.; Lu, W*.; Yu, L., Chemometric classification and bioactivity correlation of black instant coffee and coffee bean extract by chlorogenic acid profiling. Foods 2024, 13 (24), 4016.
- Sha, Y.; Chen, Y.; Li, W.; Zhang, J.; Wang, J*.; Fei, T.; Wu, D.; Lu, W.*, Low-cost, immediate, general-purpose, and high-throughput (LIGHt) smartphone colorimetric screening assay for water-soluble protein. Heliyon 2024, 10 (15).
- Zhu, L.; Fang, S.; Zhang, Y.; Sun, X.; Yang, P.; Lu, W.; Yu, L., Effects of sn-2 palmitic triacylglycerols and the ratio of OPL to OPO in human milk fat substitute on metabolic regulation in Sprague-Dawley rats. Nutrients 2024, 16 (9), 1299.
- Gao, B.; Zhang, J.; Lu, W.* Characterizing variances of adulterated extra virgin olive oils by UV-Vis spectroscopy combined with analysis of variance-projected difference resolution (ANOVA-PDR) and multivariate classification. Applied Sciences 2023, 13 (7), 4360.
- Gao, B.; Lu, W.*; Jin, M.; Chen, Y. Non-targeted metabolomics of moldy wheat by ultra-performance liquid chromatography – quadrupole time-of-flight mass spectrometry. Frontiers in Microbiology 2023, 14, 1136516.
- Chen, Y.; Gao, B.; Lu, W.* Recent Research Advancements of Coffee Quality Detection: Targeted Analyses vs. Nontargeted Fingerprinting and Related Issues. Journal of Food Quality 2023, 2023, 6156247.
- Zhu, L.; Fang, S.; Zhang, H.; Sun, X.; Yang, P.; Wan, J.; Zhang, Y.; Lu, W.; Yu, L., Total Sn-2 Palmitic Triacylglycerols and the Ratio of OPL to OPO in Human Milk Fat Substitute Modulated Bile Acid Metabolism and Intestinal Microbiota Composition in Rats. Nutrients 2023, 15 (23), 4929.
- Zhang, J.; Sun, H.; Lu, W.* Recent Advances in Analytical Detection of Olive Oil Adulteration. ACS Food Science & Technology 2022, 2(3), 415-424.
- Bhandari, S. D.; Gallegos-Peretz, T.; Wheat, T.; Jaudzems, G.; Kouznetsova, N.; Petrova, K.; Shah, D.; Hengst, D.; Vacha, E.; Lu, W.; Moore, J. C.; Metra, P.; Xie, Z.* Amino acid fingerprinting of authentic nonfat dry milk and skim milk powder and effects of spiking with selected potential adulterants. Foods 2022, 11(18), 2868-2890.
- Sun, H.; Lu, W.*; Gao, B. Non-targeted detection of butter adulteration using pointwise UHPLC-ELSD and UHPLC-UV fingerprints with chemometrics. Food Chemistry 2021, 365, 129604.
- Huang, G.; Wu, Y.; Liu, M.; Sun, X.; Lu, W.*; Gao, B.*; Wang, T.; Yu, L. Potential biomarkers for early detection of 3‑MCPD dipalmitate exposure in Sprague−Dawley rats. Journal of Agricultural and Food Chemistry 2020, 68, 9594-9602.
- Du, L.; Lu, W.; Zhang, Y.*; Gao, B.*; Yu, L. Detection of milk powder in liquid whole milk using hydrolyzed peptide and intact protein mass spectral fingerprints coupled with data fusion technologies. Food Science & Nutrition 2020, 8, 1471-1479.
- Liu, C.; Lu, W.*; Gao, B.; Kimura, H.; Li, Y.; Wang, J. Rapid identification of chrysanthemum teas by computer vision and deep learning. Food Science & Nutrition 2020, 8, 1968-1977.
- Yang, Q.; Zhang, D.; Kabeer Farha, A.; Yang, X.; Li, H.; Kong, K.; Zhang, J.; Chan, C.; Lu, W.; Croke, H.; Gan, R.* Phytochemicals, essential oils, and bioactivities of an underutilized wild fruit Cili (Rosa roxburghii). Industrial Crops and Products 2020, 143, 111928.
- He, H.; Lu, W.* High-throughput chemometric quality assessment of extra virgin olive oils using a microtiter plate reader. Sensors 2019, 19, 4169.
- Du, L.; Lu, W.*; Gao, B.*; Wang, J.; Yu, L. Authenticating raw from reconstituted milk using Fourier transform infrared spectroscopy and chemometrics. Journal of Food Quality 2019.
- Li, Y.; Yang, P.; Luo, Y.; Gao, B.; Sun, J.; Lu, W.; Liu, J.*; Chen, P.; Zhang, Y.; Yu, L.* Chemical compositions of chrysanthemum teas and their anti-inflammatory and antioxidant properties. Food Chemistry 2019, 286, 8-16.
- Lu, W., Liu, J.*, Gao, B., Lv, X., & Yu, L.* Technical note: Nontargeted detection of adulterated plant proteins in raw milk by UPLC-quadrupole time-of-flight mass spectrometric proteomics combined with chemometrics. Journal of Dairy Science 2017, 100(9), 6980-6986.
- Qin, Y.; Gao, B.; Shi, H.; Cao, J.; Yin, C.; Lu, W.; Yu, L.; Cheng, Z.* Characterization of flavonol mono-, di-, tri- and tetra-O-glycosides by ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry and its application for identification of flavonol glycosides in Viola tianschanica. Journal of Pharmaceutical and Biomedical Analysis 2017, 142, 113–124.
- Gao, B.; Luo, Y.; Lu, W.; Liu, J.; Zhang, Y.; Yu, L.* Triacylglycerol compositions of sunflower, corn and soybean oils examined with supercritical CO2 ultra-performance convergence chromatography combined with quadrupole time-of-flight mass spectrometry. Food Chemistry 2017, 218, 569-574.
- 俞良莉*; 陆维盈; 刘洁; 杜丽娟 食品非目标性检测技术. Journal of Food Science and Technology 2016, 34(6), 1-6.
- Zou, C.; Shi, H.; Liu, X.; Sheng, Y.; Ding, T.; Yan, J.; Gao, B.; Liu, J.; Lu, W.; Yu, L.* Conjugated linolenic acids and nutraceutical components in Jiaogulan (Gynostemma pentaphyllum) seeds. LWT - Food Science and Technology 2016, 68, 111-118.
- 吕夏夏; 陆维盈*; Yu, L. 运用氨基酸指纹图谱研究牛乳产地和季节变化. jk萝莉 学报（农业科学版）2016, 34(5), 50-57.
- Lu, W.; Lv, X.; Gao, B.; Shi, H.; Yu, L.* Differentiating milk and non-milk proteins by UPLC amino acid fingerprints combined with chemometric data analysis techniques. Journal of Agricultural and Food Chemistry 2015, 63, 3996-4002.
- Gao, B.; Qin, F.; Ding, T.; Chen, Y.; Lu, W.*; Yu, L.* Differentiating organically and conventionally grown oregano using ultraperformance liquid chromatography mass spectrometry (UPLC-MS), headspace gas chromatography with flame ionization detection (headspace-GC-FID), and flow injection mass spectrum (FIMS) fingerprints combined with multivariate data analysis. Journal of Agricultural and Food Chemistry 2014, 62, 8075-8084.
- Lu, W.; Jiang, Q.; Shi, H.; Niu, Y.; Gao, B.; Yu, L., Partial least-squares-discriminant analysis differentiating Chinese wolfberries by UPLC–MS and flow injection mass spectrometric (FIMS) fingerprints. Journal of Agricultural and Food Chemistry 2014, 62, 9073-9080.
- Du, L., Lu, W.*, Cai, Z., Bao, L., Hartmann, C., Gao, B., & Yu, L.* Rapid detection of milk adulteration using intact protein flow injection mass spectrometric fingerprints combined with chemometrics. Food Chemistry 2018, 240, 573-578.
- Lu, W.; Niu, Y.; Yang, H.; Sheng, Y.; Shi, H.*; Yu, L.* Simultaneous HPLC quantification of five major triterpene alcohol and sterol ferulates in rice bran oil using a single reference standard. Food Chemistry 2014, 148, 329-334.
- Zhou, Q.; Lu, W.; Niu, Y.; Liu, J.; Zhang, X.; Gao, B.; Akoh, C. C.; Shi, H.; Yu, L.* Identification and quantification of phytochemical composition and anti-inflammatory, cellular antioxidant, and radical scavenging activities of 12 plantago species. Journal of Agricultural and Food Chemistry 2013, 61, 6693-6702.
- Bi Y.; Xie Q.; Peng S.; Lu W. Slice transform based weight updating strategy for PLS. Journal of Chemometrics 2012, 26(11-12), 565-575.
- Lu, W.; Rankin J.G.; Bondra A.; Trader C.; Heeren A.; Harrington P.B. Ignitable liquid identification using gas chromatography/mass spectrometry data by projected difference resolution mapping and fuzzy rule-building expert system classification. Forensic Science International 2012, 220(1-3), 210-218.
- Lu, W.; Callahan, J.H.; Fry, F.S.; Andrzejewski, D.; Musser, S.M.; Harrington, P.B. A discriminant based charge deconvolution analysis pipeline for protein profiling of whole cell extracts using liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry. Talanta 2011, 84(4), 1180-1187.
- Lu, W.; Harrington, P.B.* Radial basis function cascade correlation networks. Algorithms 2009, 2, 1045-1068.