研究内容
- （一）延缓衰老的膳食和营养干预及其分子机制
- （二）调节免疫的膳食和营养干预及其分子机制
承担项目
- 国家自然科学基金青年项目C类
- 国家自然科学基金面上项目
- 上海市自然科学基金面上项目
- 仙乐皮肤屏障修复功能原料筛选
- 金龙鱼特异性脂肪酸的抗衰机制研究
- 仙乐抗衰机制研究
- 仙乐抗衰功效评价
- 浙江省宁波市科委项目2024
- 浙江省宁波市科委项目2025
- 金龙鱼慈善基金会项目
论文
- Peng Y, Zhang M, Zheng L, Liang Q, Li H, Chen JT, Guo H, Yoshina S, Chen YZ, Zhao X, Wu X, Liu B, Mitani S, Yu JS, Xue D. Cysteine protease cathepsin B mediates radiation-induced bystander effects. Nature. 2017 Jul 27;547(7664):458-462.(共同第一作者 IF=69.5）
- Zheng L, Wu X, Li S, Liu B, Xue D. Cathepsin B inhibitors block multiple radiation-induced side effects in C. elegans. Cell Research. 2019 Dec;29(12):1042-1045.(第一作者 IF=46.3）
- Li N, Gao X, Zheng L, Huang Q, Zeng F, Chen H, Farag MA, Zhao C. Advances in fucoxanthin chemistry and management of neurodegenerative diseases. Phytomedicine. 2022 Oct;105:154352. （中间作者 IF=6.7）
- Huang Y, Li N, Yang C, Lin Y, Wen Y, Zheng L, Zhao C. Honeybee as a food nutrition analysis model of neural development and gut microbiota. Neurosci Biobehav Rev. 2023 Oct;153:105372. （共同通讯 IF=9.0）
- You L, Huang Z, He W, Zhang L, Yu H, Zeng Y, Huang Y, Zeng S, Zheng L. Dietary alpha-lipoic acid alleviates heat stress by modulating insulin-like signaling to maintain homeostasis in C. elegans. Food Funct. 2025 Mar 31;16(7):2824-2839. （最后通讯 IF=5.6）
- Xu B, He W, Fan F, Chen S, Zhu M, Hou Y, Zheng L, Yu H, Liu Y. β-synuclein blocks α-synuclein condensate fusion to disrupt the maturation of phase separation. Cell Reports. 2025 28;44(6):115761. (共同通讯 IF=6.9)
- Wang H, Wu D, Jiang Y, Jia G, Xiao Q, Liang H, Ma N, Hu B, Zhao R, Lv H, Ma Y, Wei DQ, Zheng L, Xiao Z. The Key Flavor Substance in Zanthoxylum Preventing Alzheimer's Disease through Insulin Signaling. J Agric Food Chem. 2025 6;73(31):19631-19641. (共同通讯 IF=6.4)
- Xin Wang, Qiang Tao, Shiyin Zhao, Xing Zhang, Longnong You, Yaoyong Zeng, Lingjun Zheng, Junjie Zhang, Meng Qiao, Sirui Liu, Yingzi Li, Bo Yang, Feng Zhu. Stereoselective C(sp3)-Si/Ge bond formation via nickel-catalyzed decarboxylative couplings.Chem.2025 102713: 2451-9294 (共同通讯 IF=19.8)
- Qiu Y, Xu J, Liao W, Yang S, Wen Y, Farag MA, Zheng L, Zhao C. Ulvan derived from Ulva lactuca suppresses hepatocellular carcinoma cell proliferation through miR-542-3p-mediated downregulation of SLC35F6. Int J Biol Macromol. 2025 308:142252. （中间作者 IF=8.2）
专利著作
- Ding Xue; Yu Peng; Man Zhang; Lingjun Zheng; Qian Liang; Hanzeng Li; Jau-Song Yu; JengTing Chen ; Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiotherapy, 2022-9-27, 美国, US11452709B2
- Ding Xue; Yu Peng; Man Zhang; Lingjun Zheng; Qian Liang; Hanzeng Li; Jau-Song Yu; JengTing Chen ; Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiotherapy, 2024-2-21, 欧洲, EP 3655 015 B1
- Ding Xue; Yu Peng; Man Zhang; Lingjun Zheng; Qian Liang; Hanzeng Li; Jau-Song Yu; JengTing Chen ; Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiation therapy, 2024-12-11, 日本, JP7598137B2